CAVER - software tool for protein analysis and visualization

CAVER is a software tool for analysis and visualization of tunnels and channels in protein structures. Tunnels are void pathways leading from a cavity buried in a protein core to the surrounding solvent. Unlike tunnels, channels lead through the protein structure and their both endings are opened to the surrounding solvent. Studying of these pathways is highly important for drug design and molecular enzymology.

CAVER Analyst

CAVER provides rapid, accurate and fully automated calculation of tunnels and channels in static structures. The molecules amendable to analysis of CAVER include proteins, nucleic acids or inorganic materials.

CAVER can be used either as PyMol plugin or independent application CAVER Analyst. CAVER Analyst has been designed for easy set-up of calculation, visualization of results and efficient data analysis.

Currently the latest CAVER 3.0 command-line version performing the analysis of dynamic molecular simulations is available.

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latest news

July 14, 2014

CAVER was cited in the Journal of Biological Chemistry in the article The Combined Structural and...

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July 5, 2014

CAVER 3.0 software was cited in PNAS in the article called Structures of benzylsuccinate synthase...

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CAVER 3.0 software was cited in PLOS ONE in the article called Ensemble Generation and the Influence...

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user statistics

268 citations (Web of Knowledge)
5559 registered users
31404x CAVER downloaded