CAVER is a software tool for analysis and visualization of tunnels and channels in protein structures. Tunnels are void pathways leading from a cavity buried in a protein core to the surrounding solvent. Unlike tunnels, channels lead through the protein structure and their both endings are opened to the surrounding solvent. Studying of these pathways is highly important for drug design and molecular enzymology.

CAVER Analyst

CAVER provides rapid, accurate and fully automated calculation of tunnels and channels in static and dynamic structures. The molecules amendable to analysis of CAVER include proteins, nucleic acids, or inorganic materials.

The software is available as CAVER 3.0 command-line version, CAVER 3.0 PyMol plugin or graphical application CAVER Analyst 1.0. The latest version of CAVER enables the analysis of molecular dynamics simulations. CAVER Analyst allows easy set-up of calculation, visualization of results, and efficient visual analysis of data.



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994 citations
6071 registered users
111444x CAVER downloaded

news

CAVER was recently cited by the article Cholesterol access in cellular membranes controls Hedgehog...

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CAVER was cited in the NATURE Communications article Antibiotic export by MexB multidrug efflux...

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CAVER was recently cited by the article Ensemble-based enzyme design can recapitulate the effects...

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